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Produktnavn: |
Isobutyraldehyde |
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CAS: |
78-84-2 |
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MF: |
C4H8O |
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MW: |
72.11 |
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EINECS: |
201-149-6 |
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Product Categories: |
Carbonyl Compounds;Chemical Synthesis;Aldehydes;Building Blocks;C1 to C6;Organic Building Blocks |
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Mol File: |
78-84-2.mol |
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Melting point |
−65 °C(lit.) |
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Kokepunkt |
63 ° C (opplyst) |
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tetthet |
0,79 g / ml ved 25 ° C (opplyst) |
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damptetthet |
2,5 (mot luft) |
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damptrykk |
66 mm Hg ( 4.4 °C) |
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FEMA |
2220 | ISOBUTYRALDEHYDE |
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brytningsindeks |
n20/D 1.374(lit.) |
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Fp |
−40 ° F |
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lagringstemperatur |
2-8°C |
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solubility |
vann: løselig 11g / 100 ml ved 20 ° C (opplyst) |
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form |
Liquid |
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farge |
Clear |
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Odor |
Pungent. |
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Odor Threshold |
0.00035ppm |
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explosive limit |
1,6-11,0% (V) |
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Water Solubility |
75 g / l (20 ºC) |
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Følsom |
Luftfølsom |
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JECFA Number |
252 |
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Merck |
14,5154 |
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BRN |
605330 |
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Stabilitet: |
Stable. Refrigerate. Highly flammable. Incompatible with strong oxidizing agents, strong bases, strong acids, strong reducing agents. |
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CAS DataBase Reference |
78-84-2(CAS DataBase Reference) |
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NIST Chemistry Reference |
Propanal, 2-metyl- (78-84-2) |
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EPA Substance Registry System |
Isobutyraldehyd (78-84-2) |
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Hazard Codes |
F, Xn, Xi |
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Risk Statements |
11-22-36 |
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Safety Statements |
16-36 / 37-9-33-29-26 |
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RIDADR |
UN 2045 3/PG 2 |
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WGK Tyskland |
1 |
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RTECS |
NQ4025000 |
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F |
9-13-23 |
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Selvantennelsestemperatur |
384 °F |
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TSCA |
Ja |
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HS Code |
2912 19 00 |
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HazardClass |
3 |
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PackingGroup |
II |
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Hazardous Substances Data |
78-84-2(Hazardous Substances Data) |
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Toksisitet |
LD50 orally in rats: 3.7 g/kg (Smyth) |
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Beskrivelse |
Isobutyraldehyde, also known as 2-Methylpropanal, is an organic compound belonging to the family of aldehydes, which can be found in alcoholic beverages, tea, breads, cooked pork, spearmint oil as well as fresh fruits, such as apple, banana, cherry, etc. It is manufactured by the hydroformylation of propene, usually obtained as a side-product. It can be applied as a source for producing other chemicals, including isobutyl alcohol, neopentyl glycol as well as isobutanoic acid production and used to produce amino acids such as valine and leucine. Besides, isobutyraldehyde commonly serves as an intermediate in the field of chemical industry for manufacture of pharmaceuticals (such as Vitamin B5), crop protection products, pesticides, synthetic resins, antioxidants, vulcanisation accelerators, textile auxiliaries, perfumery and flavors. |
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Referanser |
https://pubchem.ncbi.nlm.nih.gov/compound/isobutyraldehyde#section=Top |
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Beskrivelse |
Isobutyraldehyde has a characteristic odor. Synthesized via oxidation of isobutyl alcohol with potassium dichromate and concentrated sulfuric acid. |
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Kjemiske egenskaper |
Isobutyraldehyde has a characteristic sharp, pungent odor. |
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Kjemiske egenskaper |
fargeløs væske med en ekstremt ubehagelig lukt |
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Occurrence |
Rapportert funnet inapple- og ripsaromaer og i essensielle oljer fra tobakkblader og teeblader, også i essensielle oljer av Pinus jeffreyi Murr. blader, Citrusaurantium blader og Datura stramonium. Rapportert funnet i eple, banan, søt og sur kirsebær, rips, kålrabi, gulrøtter, selleri, erter, potet, tomat, peppermynte, mais mynte og mynteolje, eddik, hvete og ryggbrød, oster, smør, yoghurt, egg, kaviar, fet fisk, kjøtt, humleolje, øl, konjakk, rom, sherry, cider, whisky, drueviner, kakao, kaffe, te, filberts, peanøtter, popcorn, havre, soyabønner, honning, sopp, macadamianøtter, blomkål, pære og eplebrennevin, ris, sukiyaki, malt, loquat, salvie, reker, trøffel, kamskjell og blekksprut |
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Bruker |
Isobutyraldehyde is used in the synthesisof cellulose esters, resins, and plasticizers;in the preparation of pantothenic acid andvaline; and in flavors. |
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Bruker |
In the synthesis of pantothenic acid, valine, leucine, cellulose esters, perfumes, flavors, plasticizers, resins, gasoline additives. |
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Definition |
CHEBI: Et medlem av klassen av propanaler som er propanal erstattet av en metylgruppe ved posisjon 2. |
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Preparation |
By oxidation of isobutyl alcohol with potassium dichromate and concentrated sulfuric acid. |
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Aroma terskelverdier |
Deteksjon: 0,4 til 43 ppm |
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Generell beskrivelse |
A clear colorless liquid with a pungent odor. Flash point of -40°F. Less dense than water and insoluble in water. Hence floats on water. Vapors are heavier than air. Used to make other chemicals. |
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Air & Water Reactions |
Meget brannfarlig. Oksideres sakte ved eksponering for luft. Stabil (mindre enn 10% nedbrytning) i fire timer når den utsettes for lys og luft i et lukket system. Stabil i to uker når den lagres under nitrogen ved temperaturer opp til 77 ° F. Uoppløselig i vann. |
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Reaktivitetsprofil |
Isobutyraldehyde can react vigorously with reducing agents, with oxidizing agents, strong bases and mineral acids. Can undergo exothermic self-condensation or polymerization reactions that are often catalyzed by acid. Generates flammable and/or toxic gases in combination with azo, diazo compounds, dithiocarbamates, nitrides, and strong reducing agents. Reacts slowly when exposed to air with air to give peroxides and other products. These reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by their products). The addition of stabilizers (antioxidants) retards autoxidation. |
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Hazard |
Highly flammable, dangerous fire and explosion risk. Irritant to skin and eyes. |
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Helserisiko |
Vapor is irritating to the eyes and mucous membranes. |
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Helserisiko |
Isobutyraldehyde is
a moderate skin and eyeirritant; the effect may be slightly greaterthan that
of n-butyraldehyde. An amounttotaling 500 mg in 24 hours produced severeskin
irritation in rabbits; 100 mg causedmoderate eye irritation. |
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Fire Hazard |
Atferd ved brann: Dampene er tyngre enn luft og kan kjøre betydelig avstand til en antennelseskilde og blinke tilbake. Branner er vanskelige å kontrollere på grunn av enkel reignition. |
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Kjemisk reaktivitet |
Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent. |
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Carcinogenicity |
Isobutyraldehyd er ikke mutagent i forskjellige stammer av S. typhimurium og er ikke-kreftfremkallende rotter og mus. |
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Purification Methods |
Tørk isobutyraldehyd med CaSO4 og bruk den umiddelbart etter destillasjon under nitrogen på grunn av den store vanskeligheten med å forhindre oksidasjon. Det kan renses gjennom syrebisulfittderivatet. [Beilstein 1 IV 3262.] |
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Avfallshåndtering |
Isobutyraldehyde is burned in a chemicalincinerator equipped with an afterburner andscrubber. |
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Forberedelsesprodukter |
1-butanol -> 2-metyl-1-propanol -> ismørsyre -> metylmetakrylat -> butyraldehyd -> 2,2-dimetyl-1,3-propandiol -> isobutyronitril -> L- Valin -> 3- (4-ISOPROPYLFENYL) ISOBUTYRALDEHYDE -> 3-metyl-2-butanon -> Rifapentin -> D - (+) - Pantotensyre kalsiumsalt -> DL-Pantolactone -> ALDICARB- OXIME -> Karbosulfan -> 2,5-dimetyl-2,4-heksadien -> 2-AMINO-3-METYLBUTANENITRIL -> FENPROPIMORPH -> 2-ISOPROPYL-6-METYL-4-PYRIMIDINOL -> D - (-) - PANTOLAKTON -> Isobutylamin -> 3-hydroksy-2,2-dimetylpropanal -> DL-valin -> 2-metylbutyl 2-metylbutyrat -> 1-KLOR-2-METYLPROPYLKLORFORMAT - > 1-KLOR-2-METYL-1-PROPEN -> 2,6-dimetyl-5-heptenal -> N, N '' - (isobutyliden) diurea -> GERANYL ISOBUTYRATE -> 2,2,4 -Trimetyl-1,3-pentandiolmono (2-metylpropanoat) -> 5-METYL-3-HEXEN-2-ONE -> Neopentylglykolmonoesterhydropivalikat |
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Raw materials |
CARBON MONOXIDE-->Potassium dichromate-->2-Methyl-1-propanol-->PROPYLENE-->Butyraldehyde-->2-Amino-3-chlorobenzoic acid |
